The Inhibin alpha chain Polyclonal Antibody (CAB1734) is a valuable tool for researchers studying the Inhibin alpha chain, a protein involved in the regulation of reproductive processes and hormone signaling. This antibody, derived from rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. By targeting the Inhibin alpha chain protein, researchers can accurately detect and analyze its expression in various cell types, making it ideal for studies in reproductive biology and endocrinology.The Inhibin alpha chain is a key player in the control of follicle-stimulating hormone (FSH) secretion, which in turn affects processes such as folliculogenesis and spermatogenesis.
Dysregulation of Inhibin alpha chain signaling has been implicated in conditions such as infertility, polycystic ovary syndrome (PCOS), and certain types of cancer. Therefore, a deeper understanding of the role of the Inhibin alpha chain is essential for developing targeted therapies and diagnostic tools for these conditions.By utilizing the Inhibin alpha chain Polyclonal Antibody (CAB1734), researchers can further explore the complex mechanisms underlying reproductive health and disease, paving the way for new advancements in fertility treatments and personalized medicine.
Product Name:
INHA Rabbit Polyclonal Antibody
SKU:
CAB1734
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Inhibin alpha (INHA) (NP_002182.1).
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients.
Purification Method:
Affinity purification
Gene ID:
3623
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using Inhibin alpha (INHA) Rabbit pAb (CAB1734) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
