The INHBE Polyclonal Antibody (PACO02000) is a valuable tool for researchers studying the role of INHBE, a member of the TGF-beta superfamily, in cellular signaling pathways. This highly specific antibody, generated in rabbits, is suitable for use in various applications, including Western blot and immunohistochemistry.INHBE, also known as inhibin beta E, is known to play a key role in the regulation of cell growth, differentiation, and development. Its involvement in various biological processes, such as embryogenesis and reproductive function, makes it an intriguing target for investigation in fields such as developmental biology and reproductive health.
By utilizing the INHBE Polyclonal Antibody, researchers can effectively detect and analyze the expression of INHBE protein in different cell types and tissues, providing valuable insights into its function and potential implications in health and disease. This antibody is a valuable tool for advancing research in areas such as endocrinology, reproductive biology, and developmental genetics.
Antibody Name:
INHBE Antibody
Antibody SKU:
PACO02000
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the C-terminal region of human Inhibin Beta-E.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
INHBE; Inhibin beta E chain; Activin beta-E chain
UniProt Protein Function:
INHBE: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Belongs to the TGF-beta family.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 12q13.3Cellular Component: extracellular spaceMolecular Function: cytokine activity; growth factor activity; hormone activity; transforming growth factor beta receptor bindingBiological Process: cell development; regulation of apoptosis; regulation of MAPKKK cascade
UniProt Protein Details:
NCBI Summary:
INHBE is a member of the activin beta family (see INHBA; MIM 147290) that plays a role in pancreatic exocrine cell growth and proliferation (Hashimoto et al., 2006 [PubMed 16426570]).[supplied by OMIM, May 2008]
