Inhibin beta A (INHBA) Rabbit Polyclonal Antibody (CAB5837)
The INHBA Polyclonal Antibody (CAB5837) is a valuable tool for researchers studying INHBA, a protein involved in various biological processes, including cell proliferation, differentiation, and tissue regeneration. This antibody is generated in rabbits and is highly specific for detecting human samples in Western blot applications. By targeting the INHBA protein, researchers can gain insights into its role in cell signaling pathways and its potential implications in diseases such as cancer and fibrosis.
INHBA, also known as activin A, is a member of the TGF-beta superfamily and is known for its role in regulating cell growth and differentiation. Dysregulation of INHBA has been linked to various diseases, making it a promising target for therapeutic interventions. By using the INHBA Polyclonal Antibody, researchers can further understand the molecular mechanisms underlying its functions and explore its potential as a therapeutic target in the treatment of various disorders.
Product Name:
Inhibin beta A (INHBA) Rabbit Polyclonal Antibody
SKU:
CAB5837
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-426 of human Inhibin beta A (INHBA) (NP_002183.1).
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients.
Purification Method:
Affinity purification
Gene ID:
3624
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Inhibin beta A (INHBA) antibody (CAB5837) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.