The INHA Polyclonal Antibody (PACO34902) is a valuable tool for researchers studying the inhibin alpha subunit, a key regulator of activin and TGF-beta signaling pathways. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the INHA protein, researchers can effectively detect and analyze its expression in various cell types, making it ideal for investigations in reproductive biology and cancer research.INHA plays a crucial role in regulating follicle-stimulating hormone production and ovarian function, making it an important target for studies on reproductive health and fertility.
Additionally, abnormalities in activin signaling, in which INHA is involved, have been linked to various types of cancer, emphasizing the significance of understanding its function in disease development and progression. This antibody facilitates the exploration of INHA's role in these physiological and pathological processes, providing valuable insights for potential therapeutic interventions.
Antibody Name:
inhA Antibody (PACO34902)
Antibody SKU:
PACO34902
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Mycobacterium tuberculosis
Immunogen:
Recombinant Mycobacterium tuberculosis Enoyl-[acyl-carrier-protein] reductase [NADH] protein (1-269AA)
Enoyl-ACP reductase of the type II fatty acid syntase (FAS-II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls (PubMed:25227413). Catalyzes the NADH-dependent reduction of the double bond of 2-trans-enoyl-[acyl-carrier protein], an essential step in the fatty acid elongation cycle of the FAS-II pathway (PubMed:7599116). Shows preference for long-chain fatty acyl thioester substrates (>C16), and can also use 2-trans-enoyl-CoAs as alternative substrates (PubMed:7599116). The mycobacterial FAS-II system utilizes the products of the FAS-I system as primers to extend fatty acyl chain lengths up to C56, forming the meromycolate chain that serves as the precursor for final mycolic acids (PubMed:25227413).
