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ING2 Monoclonal Antibody [PAT39E5AT] (CPAB0600)

SKU:
CPAB0600
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT39E5AT
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

ING2 Monoclonal Antibody [PAT39E5AT] (CPAB0600)

The ING2 Polyclonal Antibody (CPAB0600) is a crucial tool for researchers studying the ING2 protein, which is involved in various cellular processes including DNA repair, cell cycle regulation, and apoptosis. This antibody, produced in rabbits, demonstrates high specificity and sensitivity towards human samples, making it ideal for Western blotting and immunohistochemistry applications.ING2, a member of the inhibitor of growth (ING) family, has been linked to cancer development and progression, making it a promising target for cancer research.

Its role in DNA damage response and epigenetic regulation highlights its importance in understanding tumorigenesis and identifying potential therapeutic strategies. The ING2 Polyclonal Antibody enables accurate detection and analysis of the ING2 protein, facilitating research in cancer biology and molecular mechanisms underlying tumorigenesis.

Product Name:ING2 Antibody
Product Sku:CPAB0600
Size:5μg
Host Species:Mouse
Immunogen:Anti-human ING2 mAb, clone PAT39E5AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ING2 protein 1-28 amino acids purified from Ecoli.
Clone:PAT39E5AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:ING2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:Inhibitor of Growth Family, Member 2 (ING2) belongs to the inhibitor of growth (ING) family. ING family members associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and serve in DNA repair and apoptosis. ING2 appears to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, most likely by enhancing acetylation of p53/TP53. ING2 is a component of an mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity is modulated by binding to phosphoinositides (PtdInsPs).
Synonyms:Inhibitor Of Growth Family Member 2, ING1L, Inhibitor Of Growth 1-Like Protein, P33ING2, ING1Lp, P32, Inhibitor Of Growth Family Member 1-Like, Inhibitor Of Growth Protein 2, ING2.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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