The ING1 Polyclonal Antibody (CAB7904) is a valuable tool for researchers studying the tumor suppressor protein ING1. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the ING1 protein, this antibody enables the detection and analysis of ING1 in various cell types.ING1 is known to play a crucial role in regulating cell growth, apoptosis, and DNA repair, making it a key target for cancer research.
Dysregulation of ING1 has been linked to various types of cancer, underscoring the importance of studying this protein in the context of oncology. The ING1 Polyclonal Antibody is a valuable tool for investigating the mechanisms by which ING1 functions in normal and diseased cells, providing insight into potential therapeutic targets for cancer treatment.
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
Purification Method:
Affinity purification
Gene ID:
3621
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HT-29 cells using ING1 Rabbit pAb(CAB7904) at 1:500 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime:90s.
