INCA1 Antibody (PACO35230)
- SKU:
- PACO35230
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | INCA1 Antibody (PACO35230) |
Antibody SKU: | PACO35230 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Protein INCA1 protein (1-236AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO35230 at dilution of 1:100. |
Background: | Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor. Inhibits cell growth and cell proliferation and may play a role in cell cycle control (By similarity). Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth (By similarity). |
Synonyms: | Protein INCA1 (Inhibitor of CDK interacting with cyclin A1), INCA1 |
UniProt Protein Function: | INCA1: Belongs to the INCA family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Cell cycle regulationChromosomal Location of Human Ortholog: 17p13.2Cellular Component: cytoplasm; nucleusMolecular Function: cyclin-dependent protein kinase inhibitor activity; protein binding; cyclin bindingBiological Process: negative regulation of cell proliferation; negative regulation of cyclin-dependent protein kinase activity |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q0VD86 |
NCBI GenInfo Identifier: | 269847505 |
NCBI Gene ID: | 388324 |
NCBI Accession: | NP_001161457.1 |
UniProt Secondary Accession: | Q0VD86,Q6J273, Q6PKN9 |
UniProt Related Accession: | Q0VD86 |
Molecular Weight: | 26817 |
NCBI Full Name: | protein INCA1 isoform 2 |
NCBI Synonym Full Names: | inhibitor of CDK, cyclin A1 interacting protein 1 |
NCBI Official Symbol: | INCA1Â Â |
NCBI Official Synonym Symbols: | HSD45Â Â |
NCBI Protein Information: | protein INCA1 |
UniProt Protein Name: | Protein INCA1 |
UniProt Synonym Protein Names: | Inhibitor of CDK interacting with cyclin A1 |
Protein Family: | Protein |
UniProt Gene Name: | INCA1Â Â |
UniProt Entry Name: | INCA1_HUMAN |