IPO5 Rabbit Polyclonal Antibody (CAB1984)
- SKU:
- CAB1984
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
Product Name: | IPO5 Rabbit Polyclonal Antibody |
SKU: | CAB1984 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human IPO5 (NP_002262.3). |
Sequence: | AAAA AEQQ QFYL LLGN LLSP DNVV RKQA EETY ENIP GQSK ITFL LQAI RNTT AAEE ARQM AAVL LRRL LSSA FDEV YPAL PSDV QTAI KSEL LMII QMET QSSM RKKV CDIA AELA RNLI DEDG NNQW PEGL KFLF DSVS SQNV GLRE AALH IFWN FPGI FGNQ QQHY LDVI KRML VQCM QDQE HPSI RTLS ARAT AAFI LANE HNVA LFKH FADL LPGF LQAV NDSC YQND DSVL KSLV EIAD TVPK YLRP HLEA TLQL SLKL CGDT SLNN MQRQ LALE V |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | IMB3; Pse1; imp5; KPNB3; RANBP5; IPO5 |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, nucleolus. |
Calculated MW: | 124kDa |
Observed MW: | 124kDa |
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
Purification Method: | Affinity purification |
Gene ID: | 3843 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |