The IMPG1 Polyclonal Antibody (CAB16387) is a valuable tool for researchers studying the IMPG1 protein, which plays a critical role in the extracellular matrix of the eye. This antibody, raised in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the IMPG1 protein, researchers can detect and analyze this molecule in various cell types, making it ideal for studies in ophthalmology and vision research.IMPG1, also known as Interphotoreceptor Matrix Proteoglycan 1, is essential for maintaining the structure and function of the interphotoreceptor matrix in the eye.
Its involvement in retinal health makes it a key target for research into diseases like retinitis pigmentosa and age-related macular degeneration. By gaining a deeper understanding of IMPG1, researchers can identify potential therapeutic targets for these blinding conditions and develop treatments to preserve vision.Investing in the IMPG1 Polyclonal Antibody (CAB16387) is a crucial step for researchers seeking to advance our knowledge of retinal biology and develop innovative strategies for protecting vision health.
Product Name:
IMPG1 Rabbit Polyclonal Antibody
SKU:
CAB16387
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-300 of human IMPG1 (NP_001554.2).
This gene encodes a protein that is a major component of the retinal interphotoreceptor matrix. The encoded protein is a proteoglycan that is thought to play a role in maintaining viability of photoreceptor cells and in adhesion of the neural retina to the retinal pigment epithelium. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3617
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat eye, using IMPG1 Rabbit pAb (CAB16387) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.