IMPDH2 Rabbit Monoclonal Antibody (CAB9208)
- SKU:
- CAB9208
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | IMPDH2 Rabbit Monoclonal Antibody |
SKU: | CAB9208 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human IMPDH2 (P12268). |
Sequence: | QANE VRKV KKYE QGFI TDPV VLSP KDRV RDVF EAKA RHGF CGIP ITDT GRMG SRLV GIIS SRDI DFLK EEEH DCFL EEIM TKRE DLVV APAG ITLK EANE ILQR SKKG KLPI VNED DELV AIIA RTDL KKNR DYPL ASKD AKKQ LLCG AAIG THED DKYR LDLL AQAG VDVV VLDS SQGN SIFQ INMI KYIK DKYP NLQV I |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | IMPD2; IMPDH-II; H2 |
Positive Sample: | HeLa,K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 56kDa |
Observed MW: | 56kDa |
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Purification Method: | Affinity purification |
Gene ID: | 3615 |
Clone Number: | ARC1479 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |