IMPDH2 Rabbit Polyclonal Antibody (CAB5350)
- SKU:
- CAB5350
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | IMPDH2 Rabbit Polyclonal Antibody |
SKU: | CAB5350 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 215-514 of human IMPDH2 (NP_000875.2). |
Sequence: | DDEL VAII ARTD LKKN RDYP LASK DAKK QLLC GAAI GTHE DDKY RLDL LAQA GVDV VVLD SSQG NSIF QINM IKYI KDKY PNLQ VIGG NVVT AAQA KNLI DAGV DALR VGMG SGSI CITQ EVLA CGRP QATA VYKV SEYA RRFG VPVI ADGG IQNV GHIA KALA LGAS TVMM GSLL AATT EAPG EYFF SDGI RLKK YRGM GSLD AMDK HLSS QNRY FSEA DKIK VAQG VSGA VQDK GSIH KFVP YLIA GIQH SCQD IGAK SLTQ VRAM MYSG ELKF EKRT SSAQ VEGG VHSL HSYE KRLF |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:200 |
Synonyms: | IMPD2; IMPDH-II; IMPDH2 |
Positive Sample: | HeLa,K-562,Mouse spleen,Rat spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 56kDa |
Observed MW: | 56kDa |
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Purification Method: | Affinity purification |
Gene ID: | 3615 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |