The IMMT Polyclonal Antibody (CAB14107) is a vital tool for researchers studying the integral mitochondrial inner membrane protein IMMT. This polyclonal antibody, raised in rabbits, demonstrates high reactivity with human samples and is validated for use in various applications including Western blot and immunohistochemistry.IMMT plays a crucial role in mitochondrial function, specifically in the maintenance of mitochondrial morphology and cristae structure, as well as in the regulation of mitochondrial DNA replication and transcription. Dysregulation of IMMT has been linked to various mitochondrial disorders and diseases, making it a key target for research in the fields of cell biology and metabolism.
The IMMT Polyclonal Antibody enables researchers to detect and analyze the expression of the IMMT protein in different cell types and tissues, providing insights into its function and potential implications in mitochondrial-related diseases. By understanding the role of IMMT, scientists can further explore novel therapeutic strategies for treating mitochondrial disorders and improving overall cellular health.
Product Name:
IMMT Rabbit Polyclonal Antibody
SKU:
CAB14107
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human IMMT (NP_006830.2).
Enables RNA binding activity. Involved in cristae formation. Located in mitochondrial inner membrane. Part of MICOS complex.
Purification Method:
Affinity purification
Gene ID:
10989
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IMMT antibody (CAB14107) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
