ILK Rabbit Polyclonal Antibody (CAB0901)
- SKU:
- CAB0901
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ILK Rabbit Polyclonal Antibody |
SKU: | CAB0901 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ILK (NP_001014795.1). |
Sequence: | MDDI FTQC REGN AVAV RLWL DNTE NDLN QGDD HGFS PLHW ACRE GRSA VVEM LIMR GARI NVMN RGDD TPLH LAAS HGHR DIVQ KLLQ YKAD INAV NEHG NVPL HYAC FWGQ DQVA EDLV ANGA LVSI CNKY GEMP VDKA KAPL RELL RERA EKMG QNLN RIPY KDTF WKGT TRTR PRNG TLNK HSGI DFKQ LNFL TKLN ENHS GELW KGRW QGND IVVK VLKV RDWS TRKS RDFN EECP RLRI FSHP NVLP VLGA CQSP |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 |
Synonyms: | P59; ILK-1; ILK-2; p59ILK; HEL-S-28; ILK |
Positive Sample: | U-251MG,HeLa,Mouse kidney,293T,NIH/3T3,MCF7,A-549,Mouse heart,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, focal adhesion, lamellipodium, myofibril, sarcomere. |
Calculated MW: | 51kDa |
Observed MW: | 48kDa |
This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 3611 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |