The ILK Polyclonal Antibody (CAB0901) is a crucial tool for researchers studying Integrin-linked kinase (ILK), a key regulator of cell adhesion and migration. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards ILK in human samples, making it an ideal choice for Western blot applications. By targeting the ILK protein, this antibody enables accurate detection and analysis in various cell types, facilitating in-depth research in cell biology and cancer studies.ILK is a critical signaling molecule involved in multiple cellular processes, including cell survival, proliferation, and differentiation. Dysregulation of ILK has been implicated in various diseases, particularly cancer, where it promotes tumor growth and metastasis.
Understanding the mechanisms by which ILK contributes to pathogenesis can provide valuable insights for developing targeted therapies to combat cancer progression.By utilizing the ILK Polyclonal Antibody (CAB0901), researchers can delve deeper into the molecular pathways controlled by ILK, unraveling its role in normal cellular function and disease development. This antibody serves as a valuable tool for advancing scientific knowledge and potentially unlocking new treatment strategies for cancer and other related conditions.
Product Name:
ILK Rabbit Polyclonal Antibody
SKU:
CAB0901
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ILK (NP_001014795.1).
This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3611
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using ILK Rabbit pAb (CAB0901) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
