The ILF3 Rabbit Monoclonal Antibody (CAB8186) is a highly specific tool for researchers studying the ILF3 protein, which is involved in various cellular processes such as RNA processing, transcriptional regulation, and DNA repair. This antibody, generated in rabbits, has been validated for use in immunofluorescence, immunohistochemistry, and Western blot applications with human samples.ILF3, also known as interleukin enhancer binding factor 3, is a key player in gene regulation and protein interactions within the cell. Its diverse functions make it a crucial target for investigations into gene expression, RNA metabolism, and cellular signaling pathways.
Researchers in molecular biology, biochemistry, and cancer biology will find this antibody essential for studying the roles of ILF3 in different cellular processes and disease states.With its high specificity and sensitivity, the ILF3 Rabbit Monoclonal Antibody (CAB8186) provides reliable and reproducible results for research purposes. Whether exploring the mechanisms of gene regulation or investigating potential therapeutic targets in cancer, this antibody is a valuable tool for advancing scientific knowledge in the field of molecular biology.
Product Name:
ILF3 Rabbit Monoclonal Antibody
SKU:
CAB8186
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ILF3 (Q12906).
This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
3609
Clone Number:
ARC1438
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ILF3 Rabbit mAb (CAB8186) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
