ILF3 Rabbit Polyclonal Antibody (CAB2496)
- SKU:
- CAB2496
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
Product Name: | ILF3 Rabbit Polyclonal Antibody |
SKU: | CAB2496 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ILF3 (NP_036350.2). |
Sequence: | MRPM RIFV NDDR HVMA KHSS VYPT QEEL EAVQ NMVS HTER ALKA VSDW IDEQ EKGS SEQA ESDN MDVP PEDD SKEG AGEQ KTEH MTRT LRGV MRVG LVAK GLLL KGDL DLEL VLLC KEKP TTAL LDKV ADNL AIQL AAVT EDKY EILQ SVDD AAIV IKNT KEPP LSLT IHLT SPVV REEM EKVL AGET LSVN DPPD VLDR QKCL AALA SLRH AKWF QARA NGLK SCVI VIRV LRDL CTRV PTWG PLRG WPLE LLCE KSIG TANR PMGA GE |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | CBTF; DRBF; MMP4; MPP4; NF90; NFAR; NF110; NF90a; NF90b; NF90c; NFAR2; TCP80; DRBP76; NF110b; NFAR-1; NFAR-2; NFAR90; TCP110; MPP4110; NF90ctv; NFAR110; MPHOSPH4; NF-AT-90; ILF3 |
Positive Sample: | Hep G2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, nucleolus. |
Calculated MW: | 95kDa |
Observed MW: | 95kDa/120 kDa |
This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 3609 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |