The IL9R Polyclonal Antibody (CAB6630) offered by Assay Genie is a valuable tool for research involving the IL9R protein, which plays a crucial role in immune regulation and allergic reactions. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for studies in immunology and cancer research. IL9R, also known as interleukin-9 receptor, is involved in the modulation of immune responses and has been implicated in various inflammatory conditions and autoimmune disorders. By targeting IL9R, researchers can gain insights into the mechanisms underlying these diseases and potentially develop novel therapeutic strategies.
The IL9R Polyclonal Antibody enables the detection and analysis of IL9R protein in different cell types, making it a versatile tool for investigating the role of IL9R in immune function and disease pathology. Its use in Western blot applications allows for accurate and reliable data, paving the way for advancements in the field of immunology and personalized medicine.
Product Name:
IL9R Rabbit Polyclonal Antibody
SKU:
CAB6630
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IL9R (XP_011529456.1).
Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
57kDa
Observed MW:
57kDa
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3581
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using IL9R Rabbit pAb (CAB6630) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
