CD127/IL7R Rabbit Polyclonal Antibody (CAB1230)
- SKU:
- CAB1230
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CD127/IL7R Rabbit Polyclonal Antibody |
SKU: | CAB1230 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-239 of human CD127/IL7R (NP_002176.2). |
Sequence: | ESGY AQNG DLED AELD DYSF SCYS QLEV NGSQ HSLT CAFE DPDV NITN LEFE ICGA LVEV KCLN FRKL QEIY FIET KKFL LIGK SNIC VKVG EKSL TCKK IDLT TIVK PEAP FDLS VVYR EGAN DFVV TFNT SHLQ KKYV KVLM HDVA YRQE KDEN KWTH VNLS STKL TLLQ RKLQ PAAM YEIK VRSI PDHY FKGF WSEW SPSY YFRT PEIN NSSG EMD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | ILRA; CD127; IL7RA; CDW127; IMD104; sIL-7R; lnc-IL7R; IL7Ralpha; IL-7Ralpha; IL-7R-alpha; CD127/IL7R |
Positive Sample: | Raji,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Secreted, Single-pass type I membrane protein, Single-pass type I membrane protein. |
Calculated MW: | 52kDa |
Observed MW: | 50kDa |
The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.
Purification Method: | Affinity purification |
Gene ID: | 3575 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |