The IL7 Monoclonal Antibody (CAB22562) offered by AssayGenie is a valuable tool for researchers studying interleukin 7 (IL7), a crucial cytokine involved in immune regulation and the development of lymphoid cells. This monoclonal antibody is highly specific to IL7 and has been validated for use in various applications, including Western blotting and immunohistochemistry.IL7 plays a key role in T cell development and homeostasis, making it an important target for research into immune disorders, cancer, and autoimmune diseases.
The IL7 Monoclonal Antibody enables precise detection and analysis of IL7 protein expression in cell samples, providing researchers with valuable insights into its function and potential therapeutic applications.Whether investigating the role of IL7 in immune system function or exploring its implications in disease pathology, the IL7 Monoclonal Antibody from AssayGenie is a reliable and efficient tool for advancing your research in immunology and beyond.
Product Name:
IL7 Monoclonal Antibody
SKU:
CAB22562
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-177 of human IL7 (NP_000871.1).
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. IL7 is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. IL7 plays an essential role in lymphoid cell survival, and in the maintenance of naive and memory T cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can be a potent inducer of proinflammatory cytokines and chemokines which may defend against the infection, but may also mediate destructive lung injury. Elevated serum IL7 levels, together with several other circulating cytokines and chemokines, has been found to be associated with the severity of Coronavirus Disease 19 (COVID-19).
Purification Method:
Affinity purification
Gene ID:
3574
Clone Number:
ARC57481
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded mouse lung using IL7 Rabbit mAb (CAB22562) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
