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IL6 Polyclonal Antibody (CAB24522)

SKU:
CAB24522
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
  • Western blot analysis of Recombinant mouse IL6 Protein(10ng/100ng), using IL6 Rabbit pAb (CAB24522) at 1:400 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
  • IL6 Polyclonal Antibody (CAB24522)
€129 - €359

Description

IL6 Polyclonal Antibody (CAB24522)

The IL6 Polyclonal Antibody is a valuable tool for researchers studying Interleukin-6 (IL-6), a cytokine with diverse functions in the immune response, inflammation, and hematopoiesis. This antibody, produced in rabbits, is highly specific to IL-6 and has been validated for Western blot applications in human samples.IL-6 is a key mediator of the acute phase response and plays a crucial role in the regulation of immune responses, with implications in various diseases including cancer, autoimmune disorders, and inflammatory conditions.

By targeting IL-6, researchers can gain insights into its role in disease pathology and potentially identify new therapeutic strategies.With its high reactivity and specificity for IL-6, the IL6 Polyclonal Antibody is an essential tool for studying the function and regulation of this important cytokine in both normal and disease states. Its versatility and reliability make it a valuable asset for immunology and cancer research studies.

Product Name:IL6 Polyclonal Antibody
Product Code:CAB24522
Reactivity:Mouse
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Mouse
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:Recombinant mouse IL6 Protein(100ng), Recombinant mouse IL6 Protein(10ng)

This gene encodes a member of the interleukin family of cytokines that have important functions in immune response, hematopoiesis, inflammation and the acute phase response. The ectopic overexpression of the encoded protein in mice results in excessive plasma cells in circulation, leading to death. Mice lacking the encoded protein exhibit abnormalities in hepatic acute phase response, some immune mechanisms, bone resorption in response to estrogen, liver regeneration and wound healing. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 25-211 of mouse IL6 (NP_112445.1).
Sequence:FPTSQ VRRGD FTEDT TPNRP VYTTS QVGGL ITHVL WEIVE MRKEL CNGNS DCMNN DDALA ENNLK LPEIQ RNDGC YQTGY NQEIC LLKIS SGLLE YHSYL EYMKN NLKDN KKDKA RVLQR DTETL IHIFN QEVKD LHKIV LPTPI SNALL TDKLE SQKEW LRTKT IQFIL KSLEE FLKVT LRSTR QT
Synonyms:Il-6
Calculated MW:24kDa
Observed MW:25-35kDa

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