IL6 Monoclonal Antibody (CAB22222)
- SKU:
- CAB22222
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | IL6 Monoclonal Antibody |
SKU: | CAB22222 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human IL6 (NP_000591.1). |
Sequence: | MNSF STSA FGPV AFSL GLLL VLPA AFPA PVPP GEDS KDVA APHR QPLT SSER IDKQ IRYI LDGI SALR KETC NKSN MCES SKEA LAEN NLNL PKMA EKDG CFQS GFNE ETCL VKII TGLL EFEV YLEY LQNR FESS EEQA RAVQ MSTK VLIQ FLQK KAKN LDAI TTPD PTTN ASLL TKLQ AQNQ WLQD MTTH LILR SFKE FLQS SLRA LRQM |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2; IL6 |
Positive Sample: | HUVEC |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted |
Calculated MW: | 24kDa |
Observed MW: | 24kDa |
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2).
Purification Method: | Affinity purification |
Gene ID: | 3569 |
Clone Number: | ARC5093-01 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |