The IL6 Monoclonal Antibody (CAB22222) is a valuable tool for researchers studying Interleukin-6 (IL6), a cytokine involved in various immune responses and inflammation processes. This antibody, produced using hybridoma technology, specifically targets IL6 and has been validated for use in a variety of applications including ELISA, immunofluorescence, and immunohistochemistry.IL6 is a key player in the immune system, playing a crucial role in the regulation of immune responses, inflammation, and hematopoiesis. Dysregulation of IL6 has been linked to various diseases including rheumatoid arthritis, inflammatory bowel disease, and cancer.
By using the IL6 Monoclonal Antibody, researchers can further understand the function and regulation of IL6 in both normal and disease states, leading to potential therapeutic interventions.Overall, the IL6 Monoclonal Antibody (CAB22222) is a reliable tool for researchers interested in studying the role of IL6 in inflammation, immune response, and disease pathogenesis. Its specificity and sensitivity make it a valuable asset in the fields of immunology, oncology, and inflammatory disease research.
Product Name:
IL6 Monoclonal Antibody
SKU:
CAB22222
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human IL6 (NP_000591.1).
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2).
Purification Method:
Affinity purification
Gene ID:
3569
Clone Number:
ARC5093-01
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from HUVEC cells, using IL6 Rabbit mAb (CAB22222) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
