IL5RA Rabbit Polyclonal Antibody (CAB8552)
- SKU:
- CAB8552
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | IL5RA Rabbit Polyclonal Antibody |
SKU: | CAB8552 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-335 of human IL5RA (NP_783855.1). |
Sequence: | ADLL PDEK ISLL PPVN FTIK VTGL AQVL LQWK PNPD QEQR NVNL EYQV KINA PKED DYET RITE SKCV TILH KGFS ASVR TILQ NDHS LLAS SWAS AELH APPG SPGT SIVN LTCT TNTT EDNY SRLR SYQV SLHC TWLV GTDA PEDT QYFL YYRY GSWT EECQ EYSK DTLG RNIA CWFP RTFI LSKG RDWL AVLV NGSS KHSA IRPF DQLF ALHA IDQI NPPL NVTA EIEG TRLS IQWE KPVS AFPI HCFD YEVK IHNT RNGY LQIE KLMT NAFI SIID DLSK YDVQ VRAA VSSM CREA GLWS EWSQ PIYV GFSR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | IL5R; CD125; CDw125; HSIL5R3; IL5RA |
Positive Sample: | HL-60,B cells,U-87MG,Mouse liver,Mouse lung,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 48kDa |
Observed MW: | 76kDa |
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
Purification Method: | Affinity purification |
Gene ID: | 3568 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |