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IL4 Monoclonal Antibody (CAB24733)

SKU:
CAB24733
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$167 - $635
Frequently bought together:

Description

IL4 Monoclonal Antibody (CAB24733)

The IL4 Monoclonal Antibody (CAB24733) is a valuable tool for research involving IL4, a cytokine that plays a key role in regulating the immune response. This monoclonal antibody, produced using hybridoma technology, is highly specific for IL4 and is validated for use in various applications, including Western blot and immunohistochemistry.IL4 is known for its ability to promote the differentiation of naive T cells into Th2 cells, which are involved in allergic and inflammatory responses. It also plays a role in B cell activation and antibody production.

The IL4 Monoclonal Antibody binds specifically to IL4, allowing researchers to detect and analyze its expression in different cell types and tissues.With its high specificity and sensitivity, the IL4 Monoclonal Antibody is an essential tool for studying the role of IL4 in various immune-related processes, including allergy, asthma, and autoimmune diseases. By understanding the function of IL4, researchers can develop targeted therapies to modulate immune responses effectively in these conditions.

Product Name:IL4 Monoclonal Antibody
Product Code:CAB24733
Reactivity:Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC61989
Reactivity:Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:1000-1:5000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Recombinant Mouse IL-4 Protein, Mouse testis, Rat thymus
Cellular Location:External side of plasma membrane, Extracellular space

Enables cytokine activity. Involved in several processes, including innate immune response in mucosa; negative regulation of white fat cell proliferation; and regulation of gene expression. Acts upstream of or within several processes, including T-helper cell differentiation; positive regulation of macromolecule metabolic process; and regulation of leukocyte activation. Located in external side of plasma membrane and extracellular space. Is expressed in several structures, including brain; colon; hemolymphoid system; liver; and placenta. Used to study Sjogren's syndrome; atopic dermatitis; and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including asthma (multiple); autoimmune disease (multiple); hepatitis B; hepatitis C; and pancreatic cancer (multiple). Orthologous to human IL4 (interleukin 4).

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 21-140 of mouse IL4 (NP_067258.1).
Sequence:HIHGC DKNHL REIIG ILNEV TGEGT PCTEM DVPNV LTATK NTTES ELVCR ASKVL RIFYL KHGKT PCLKK NSSVL MELQR LFRAF RCLDS SISCT MNESK STSLK DFLES LKSIM QMDYS
Synonyms:Il-4, BSF-1
Calculated MW:16kDa
Observed MW:16kDa/18kDa

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