The IL36A Polyclonal Antibody (CAB8207) is a valuable tool for researchers studying the IL36A cytokine, a member of the IL-1 family known for its role in inflammatory responses and autoimmune diseases. This antibody, raised in rabbits, is highly specific to IL36A and has been validated for use in various applications including Western blot and immunohistochemistry.IL36A is a potent pro-inflammatory cytokine that plays a critical role in the regulation of immune responses and inflammatory pathways. Dysregulation of IL36A is associated with a variety of inflammatory conditions such as psoriasis, rheumatoid arthritis, and inflammatory bowel disease.
By targeting IL36A, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for treatment.Overall, the IL36A Polyclonal Antibody (CAB8207) is a reliable tool for researchers investigating the role of IL36A in immune responses and inflammatory diseases. Its high specificity and sensitivity make it an ideal choice for studies in immunology, autoimmunity, and inflammation.
Product Name:
IL36A Rabbit Polyclonal Antibody
SKU:
CAB8207
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-158 of human IL36A (NP_055255.1).
The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.
Purification Method:
Affinity purification
Gene ID:
27179
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IL36A antibody (CAB8207) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
