IL32 Antibody (PACO46378)
- SKU:
- PACO46378
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
IL32 Antibody (PACO46378)
The IL32 Polyclonal Antibody (PAC046378) is a valuable tool for researchers studying IL32, a pro-inflammatory cytokine with diverse roles in immune responses. This antibody, generated in rabbits, is highly specific to human IL32 and has been validated for use in Western blot applications. By binding to IL32 protein, this antibody enables precise detection and analysis in a variety of cell types, making it a versatile tool for immunology and cancer research.IL32 is known for its involvement in inflammatory processes, playing a role in the regulation of immune responses and inflammation. Its diverse functions make it a target of interest for studies on diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Research into IL32 activity is essential for the development of therapies that target or modulate immune responses in these pathological contexts.Overall, the IL32 Polyclonal Antibody offers researchers a reliable and effective tool for investigating the functions of IL32 in various biological processes. Its high reactivity and specificity make it a valuable asset for studies aimed at understanding the complex roles of IL32 in immune regulation and disease progression.
| Antibody Name: | IL32 Antibody (PACO46378) |
| Antibody SKU: | PACO46378 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Interleukin-32 protein (31-234AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO46378 at dilution of 1:100. |
 | Immunofluorescent analysis of HepG2 cells using PACO46378 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-α and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. |
| Synonyms: | Interleukin-32 (IL-32) (Natural killer cells protein 4) (Tumor necrosis factor alpha-inducing factor), IL32, NK4 TAIF |
| UniProt Protein Function: | IL32: Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF- alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion; Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: extracellular space; membrane Molecular Function:protein binding; cytokine activity Biological Process: defense response; immune response; cell adhesion |
| NCBI Summary: | This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P24001 |
| NCBI GenInfo Identifier: | 61658632 |
| NCBI Gene ID: | 9235 |
| NCBI Accession: | NP_001012650.1 |
| UniProt Related Accession: | P24001 |
| Molecular Weight: | |
| NCBI Full Name: | interleukin-32 isoform B |
| NCBI Synonym Full Names: | interleukin 32 |
| NCBI Official Symbol: | IL32Â Â |
| NCBI Official Synonym Symbols: | NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; IL-32beta; IL-32alpha; IL-32delta; IL-32gamma  |
| NCBI Protein Information: | interleukin-32 |
| UniProt Protein Name: | Interleukin-32 |
| UniProt Synonym Protein Names: | Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor |
| Protein Family: | Interleukin |
| UniProt Gene Name: | IL32Â Â |
| UniProt Entry Name: | IL32_HUMAN |
| Antibodies | ELISA Kits |
| IL32 Antibody (PACO00961) | Human IL-32 ELISA Kit (HUFI01624) |
| IL32 Antibody (PACO09935) | Human IL-32 CLIA Kit (HUES00175) |
| Human IL-32 ELISA Kit (HUES01473) | |
| Human IL-32 ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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