IL32 Antibody (PACO09935)
- SKU:
- PACO09935
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
IL32 Antibody (PACO09935)
The IL32 Polyclonal Antibody (PACO09935) is a valuable tool for researchers studying IL32, a cytokine involved in inflammation and immune response regulation. This rabbit-raised antibody is highly specific to human samples and has been validated for use in Western blot applications, allowing for the detection and analysis of IL32 protein in various cell types.IL32, also known as interleukin-32, plays a crucial role in immune modulation and has been implicated in various inflammatory conditions, autoimmune diseases, and cancer progression. Its ability to regulate cytokine production and influence immune cell function makes it a promising target for therapeutic interventions aimed at controlling immune responses in disease settings.
By using the IL32 Polyclonal Antibody, researchers can gain insight into the role of IL32 in immune regulation and its potential as a therapeutic target in conditions characterized by dysregulated inflammation. This antibody is a valuable tool for studies in immunology, cancer research, and autoimmune disorders, providing a deeper understanding of the mechanisms underlying these diseases.
| Antibody Name: | IL32 Antibody (PACO09935) |
| Antibody SKU: | PACO09935 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Human IL32 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | interleukin 32;IL32;IL-32alpha;IL-32beta;IL-32delta;IL-32gamma;NK4;TAIF;TAIFa;TAIFb;TAIFc;TAIFd ; |
| UniProt Protein Function: | IL32: Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF- alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion; Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: extracellular space; membrane Molecular Function:protein binding; cytokine activity Biological Process: defense response; immune response; cell adhesion |
| NCBI Summary: | This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P24001 |
| NCBI GenInfo Identifier: | 61658632 |
| NCBI Gene ID: | 9235 |
| NCBI Accession: | NP_001012650.1 |
| UniProt Related Accession: | P24001 |
| Molecular Weight: | |
| NCBI Full Name: | interleukin-32 isoform B |
| NCBI Synonym Full Names: | interleukin 32 |
| NCBI Official Symbol: | IL32Â Â |
| NCBI Official Synonym Symbols: | NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; IL-32beta; IL-32alpha; IL-32delta; IL-32gamma  |
| NCBI Protein Information: | interleukin-32 |
| UniProt Protein Name: | Interleukin-32 |
| UniProt Synonym Protein Names: | Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor |
| Protein Family: | Interleukin |
| UniProt Gene Name: | IL32Â Â |
| UniProt Entry Name: | IL32_HUMAN |
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