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IL32 Antibody (PACO00961)

SKU:
PACO00961
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
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Description

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IL32 Antibody (PACO00961)

The IL32 Polyclonal Antibody (PACO00961) is a vital tool for researchers studying the IL32 protein, which plays a significant role in immune regulation and inflammatory responses. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications, enabling precise detection and analysis of IL32 in various cell types.IL32, also known as interleukin-32, is a pro-inflammatory cytokine involved in the activation of immune cells and the regulation of inflammatory pathways. Its role in immune response modulation makes it a promising target for research in areas such as immunology, infectious diseases, and autoimmune disorders.

By understanding the function of IL32, researchers can uncover potential therapeutic strategies for treating conditions characterized by dysregulated immune responses.Overall, the IL32 Polyclonal Antibody (PACO00961) is a valuable tool for scientists looking to investigate the role of IL32 in health and disease, providing critical insights into immune regulation and inflammation pathways.

Antibody Name:IL32 Antibody
Antibody SKU:PACO00961
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:Human
Immunogen:synthesized peptide derived from the C-terminal region of human IL-32.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:IL32; NK4; TAIF; Interleukin-32; IL-32; Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor
UniProt Protein Function:IL32: Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF- alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. 5 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Cell adhesion; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: extracellular space; membrane

Molecular Function:protein binding; cytokine activity

Biological Process: defense response; immune response; cell adhesion

NCBI Summary:This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
UniProt Code:P24001
NCBI GenInfo Identifier:61658632
NCBI Gene ID:9235
NCBI Accession:NP_001012650.1
UniProt Related Accession:P24001
Molecular Weight:
NCBI Full Name:interleukin-32 isoform B
NCBI Synonym Full Names:interleukin 32
NCBI Official Symbol:IL32  
NCBI Official Synonym Symbols:NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; IL-32beta; IL-32alpha; IL-32delta; IL-32gamma  
NCBI Protein Information:interleukin-32
UniProt Protein Name:Interleukin-32
UniProt Synonym Protein Names:Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor
Protein Family:Interleukin
UniProt Gene Name:IL32  
UniProt Entry Name:IL32_HUMAN

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