The IL31 Polyclonal Antibody (CAB14982) is an essential tool for researchers studying interleukin-31 (IL-31), a cytokine involved in inflammatory and immune responses. This antibody, produced in rabbits, has high specificity for detecting IL-31 in human samples and has been validated for use in Western blot applications.IL-31 is known for its role in promoting inflammation and itching in conditions such as atopic dermatitis and allergic diseases. By targeting IL-31 with this polyclonal antibody, researchers can gain insights into the signaling pathways and mechanisms regulated by this cytokine, aiding in the development of new therapies for inflammatory and allergic disorders.
With its high reactivity and reliability in Western blotting, the IL31 Polyclonal Antibody (CAB14982) is an invaluable tool for studies investigating the function of IL-31 in various biological processes, making it a key asset for immunology and inflammation research.
Product Name:
IL31 Rabbit Polyclonal Antibody
SKU:
CAB14982
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-164 of human IL31 (NP_001014358.1).
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).
Purification Method:
Affinity purification
Gene ID:
386653
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using IL31 Rabbit pAb (CAB14982) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
