IL31 Rabbit Polyclonal Antibody (CAB14982)
- SKU:
- CAB14982
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | IL31 Rabbit Polyclonal Antibody |
SKU: | CAB14982 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-164 of human IL31 (NP_001014358.1). |
Sequence: | SHTL PVRL LRPS DDVQ KIVE ELQS LSKM LLKD VEEE KGVL VSQN YTLP CLSP DAQP PNNI HSPA IRAY LKTI RQLD NKSV IDEI IEHL DKLI FQDA PETN ISVP TDTH ECKR FILT ISQQ FSEC MDLA LKSL TSGA QQAT T |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | IL-31; IL31 |
Positive Sample: | 293T,HT-29,Mouse spleen,Mouse kidney,Mouse thymus,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 18kDa |
Observed MW: | 18kDa |
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).
Purification Method: | Affinity purification |
Gene ID: | 386653 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |