The Interleukin-3 Polyclonal Antibody (CAB5671) is specifically designed for research involving Interleukin-3 (IL-3), a cytokine that regulates hematopoiesis, immune responses, and inflammation. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. It binds specifically to the IL-3 protein, allowing for accurate detection and analysis in various cell types, making it ideal for studies in immunology, hematology, and inflammation research.IL-3 is a key cytokine involved in the growth and differentiation of multiple hematopoietic cell lineages, making it a crucial target for research in various diseases such as leukemia, autoimmune disorders, and inflammatory conditions.
Understanding the role of IL-3 in immune responses and hematopoiesis is essential for the development of targeted therapies and treatment strategies for these conditions.Overall, the Interleukin-3 Polyclonal Antibody (CAB5671) provides researchers with a valuable tool for studying the functions and mechanisms of IL-3 in various biological processes, ultimately contributing to advancements in the field of immunology and disease research.
Product Name:
IL3 Rabbit Polyclonal Antibody
SKU:
CAB5671
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-152 of human IL3 (NP_000579.2).
The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
Purification Method:
Affinity purification
Gene ID:
3562
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IL3 antibody (CAB5671) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.