Il2rb Antibody (PACO27609)
- SKU:
- PACO27609
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Il2rb Antibody (PACO27609)
The IL2RB Polyclonal Antibody (PACO27609) is a valuable tool for research involving IL2RB, a critical receptor involved in immune signaling and regulation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blotting. By binding to the IL2RB protein, researchers can detect and analyze its expression in different cell types, making it an ideal choice for studies in immunology, inflammation, and cancer research.IL2RB, also known as CD122, is essential for the function of interleukin-2 (IL-2), a key cytokine involved in immune responses and T cell regulation. By targeting IL2RB, researchers can gain insights into the role of IL-2 signaling in the immune system and its impact on diseases such as cancer, autoimmune disorders, and infectious diseases.
Understanding the function of IL2RB is crucial for developing targeted therapies that modulate immune responses in various pathological conditions.Overall, the IL2RB Polyclonal Antibody (PACO27609) is a versatile tool for researchers investigating the complex interactions of the immune system and the potential therapeutic implications for various diseases. Its high specificity and sensitivity make it an invaluable asset for studies aiming to unravel the roles of IL2RB in immune regulation and disease pathogenesis.
| Antibody Name: | Il2rb Antibody (PACO27609) |
| Antibody SKU: | PACO27609 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Interleukin-2 receptor subunit β protein (24-240AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | Interleukin-2 receptor subunit β (IL-2 receptor subunit beta) (IL-2R subunit beta) (IL-2RB) (High affinity IL-2 receptor subunit beta) (p70-75) (CD antigen CD122), Il2rb |
| UniProt Protein Function: | IL2RB: Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation. Interacts with HTLV-1 accessory protein p12I. Belongs to the type I cytokine receptor family. Type 4 subfamily. |
| UniProt Protein Details: | Protein type:Receptor, cytokine; Membrane protein, integral Cellular Component: cell surface; external side of plasma membrane; integral to membrane; membrane Molecular Function:hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-2 binding; interleukin-2 receptor activity Biological Process: cytokine and chemokine mediated signaling pathway; natural killer cell activation; negative regulation of apoptosis |
| NCBI Summary: | The interleukin 2 receptor is composed of alpha and beta subunits. The beta subunit encoded by this gene is very homologous to the human beta subunit and also shows structural similarity to other cytokine receptors. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P16297 |
| NCBI GenInfo Identifier: | 6680427 |
| NCBI Gene ID: | 16185 |
| NCBI Accession: | NP_032394.1 |
| UniProt Secondary Accession: | P16297,Q3TZT2, |
| UniProt Related Accession: | P16297 |
| Molecular Weight: | 27.1 kDa |
| NCBI Full Name: | interleukin-2 receptor subunit beta |
| NCBI Synonym Full Names: | interleukin 2 receptor, beta chain |
| NCBI Official Symbol: | Il2rb  |
| NCBI Official Synonym Symbols: | p70; CD122; IL15Rbeta; Il-2Rbeta; IL-15Rbeta; Il-2/15Rbeta  |
| NCBI Protein Information: | interleukin-2 receptor subunit beta |
| UniProt Protein Name: | Interleukin-2 receptor subunit beta |
| UniProt Synonym Protein Names: | High affinity IL-2 receptor subunit beta; p70-75; CD_antigen: CD122 |
| UniProt Gene Name: | Il2rb  |
| UniProt Entry Name: | IL2RB_MOUSE |
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