The IL23R Polyclonal Antibody (CAB1613) is a crucial tool for research focusing on the IL23R protein, a key player in the regulation of the immune system. This antibody, produced in rabbits, has high reactivity with human samples and is specifically validated for use in Western blot applications. By binding to the IL23R protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for studies in immunology and cancer research.IL23R is a crucial receptor involved in the signaling pathway of interleukin-23, a cytokine that plays a significant role in promoting inflammation and autoimmune responses.
The receptor's involvement in immune system regulation makes it a valuable target for research into autoimmune disorders, inflammatory conditions, and cancer. Understanding the function of IL23R is essential for developing targeted therapies that can modulate immune responses in these disease contexts.In summary, the IL23R Polyclonal Antibody is a valuable asset for researchers studying the IL23R protein and its role in immune regulation and disease processes. Its high reactivity and specificity make it a reliable tool for detecting and analyzing IL23R in various experimental settings.
Product Name:
IL23R Rabbit Polyclonal Antibody
SKU:
CAB1613
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 510-629 of human IL23R (NP_653302.2).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
72kDa
Observed MW:
72kDa
The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.
Purification Method:
Affinity purification
Gene ID:
149233
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from K-562 cells, using IL23R Rabbit pAb (CAB1613) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
