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IL2 Monoclonal Antibody (CAB23990)

SKU:
CAB23990
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
IF
€139 - €529
Frequently bought together:

Description

Product Name:IL2 Monoclonal Antibody
Product Code:CAB23990
Reactivity:Human
Applications:Western blotting, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC55030
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting, Immunofluorescence
Recommended Dilution:WB 1:3000-1:4000, IF/ICC 1:100-1:500
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Recombinant Human IL-2 Protein
Cellular Location:Secreted

This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

Immunogen:Recombinant fusion protein containing a sequence corresponding to aminoacids 21-153 of human IL2(NP_000577.2).
Sequence:APTSS STKKT QLQLE HLLLD LQMIL NGINN YKNPK LTRML TFKFY MPKKA TELKH LQCLE EELKP LEEVL NLAQS KNFHL RPRDL ISNIN VIVLE LKGSE TTFMC EYADE TATIV EFLNR WITFC QSIIS TLT
Synonyms:IL-2, TCGF, lymphokine
Calculated MW:17kDa
Observed MW:16kDa/18kDa

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