The IL2 Monoclonal Antibody (CAB22200) is a crucial tool for researchers studying IL2, a key cytokine involved in regulating the immune system and promoting T cell growth and activation. This monoclonal antibody, developed for use in various applications including ELISA, immunofluorescence, and immunohistochemistry, specifically targets IL2, allowing for precise detection and measurement in experimental settings.IL2, also known as interleukin-2, plays a vital role in the body's immune response by stimulating the proliferation of T cells and enhancing their cytotoxic activity against infected or malignant cells.
Dysregulation of IL2 signaling has been implicated in various immune-related disorders, making it a valuable target for therapeutic interventions and further research.By utilizing the IL2 Monoclonal Antibody (CAB22200), researchers can gain valuable insights into the function and expression of IL2 in different cell types and disease states, paving the way for the development of novel treatments for immune-related conditions such as cancer, autoimmune diseases, and chronic inflammatory disorders.
Product Name:
IL2 Monoclonal Antibody
SKU:
CAB22200
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-169 of mouse IL2 (NP_032392.1).
Enables cytokine activity and interleukin-2 receptor binding activity. Involved in negative regulation of T-helper 17 cell differentiation. Acts upstream of or within several processes, including extrinsic apoptotic signaling pathway in absence of ligand; positive regulation of macromolecule metabolic process; and regulation of lymphocyte activation. Located in extracellular space. Is expressed in liver; omental bursa; thymus; and thymus primordium. Used to study Sjogren's syndrome and inflammatory bowel disease. Human ortholog(s) of this gene implicated in several diseases, including Takayasu's arteritis; auditory system disease (multiple); autoimmune disease (multiple); carcinoma (multiple); and neurodegenerative disease (multiple). Orthologous to human IL2 (interleukin 2).
Purification Method:
Affinity purification
Gene ID:
16183
Clone Number:
ARC55614
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of recombinant mouse IL-2 protein, using IL2 Rabbit mAb (CAB22200) at1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 10ng per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 0.2s.
