IL1RA Rabbit Polyclonal Antibody (CAB16385)
- SKU:
- CAB16385
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | IL1RA Rabbit Polyclonal Antibody |
SKU: | CAB16385 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-159 of human IL1RA (NP_000568.1). |
Sequence: | MALE TICR PSGR KSSK MQAF RIWD VNQK TFYL RNNQ LVAG YLQG PNVN LEEK IDVV PIEP HALF LGIH GGKM CLSC VKSG DETR LQLE AVNI TDLS ENRK QDKR FAFI RSDS GPTT SFES AACP GWFL CTAM EADQ PVSL TNMP DEGV MVTK FYFQ EDE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA |
Positive Sample: | Mouse pancreas |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Secreted. |
Calculated MW: | 20kDa |
Observed MW: | 20kDa |
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Purification Method: | Affinity purification |
Gene ID: | 3557 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |