The IL1RL1 Polyclonal Antibody (CAB1913) is designed for research involving IL1RL1, also known as IL-1 receptor-like 1, a cell surface protein belonging to the interleukin-1 receptor family. IL1RL1 is known to play a crucial role in inflammatory responses and immune regulation. This antibody, generated in rabbits, is highly specific to human IL1RL1 and has been validated for use in applications such as Western blotting. By binding to the IL1RL1 protein, this antibody enables the detection and analysis of IL1RL1 expression in various cell types, making it an invaluable tool for studies in immunology, inflammation, and related fields.
IL1RL1 is a key player in immune responses and has been implicated in diseases such as asthma, allergies, and autoimmune disorders. Understanding the function and regulation of IL1RL1 is essential for the development of targeted therapies and interventions to manage these conditions effectively. The IL1RL1 Polyclonal Antibody can help researchers further unravel the role of IL1RL1 in health and disease, paving the way for new treatment strategies and advancements in medical research.
Product Name:
IL1RL1 Rabbit Polyclonal Antibody
SKU:
CAB1913
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-328 of human IL1RL1 (NP_057316.3).
Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
63kDa
Observed MW:
30kDa/41kDa/70kDa
The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
9173
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse brain, using IL1RL1 Rabbit pAb (CAB1913).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
