IL1RAPL1 Rabbit Polyclonal Antibody (CAB3378)
- SKU:
- CAB3378
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | IL1RAPL1 Rabbit Polyclonal Antibody |
SKU: | CAB3378 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-210 of human IL1RAPL1 (NP_055086.1). |
Sequence: | SISL TVGE NDTG LCYN SKMK YFEK AELS KSKE ISCR DIED FLLP TREP EILW YKEC RTKT WRPS IVFK RDTL LIRE VRED D |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | IL1R8; MRX10; MRX21; MRX34; OPHN4; IL1RAPL; TIGIRR-2; IL1RAPL-1; IL-1RAPL-1; IL-1-RAPL-1; IL1RAPL1 |
Positive Sample: | A-431,Mouse brain,Mouse heart,Rat brain,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cell projection, Cytoplasm, Single-pass type I membrane protein, axon, dendrite. |
Calculated MW: | 80kDa |
Observed MW: | 90kDa |
The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signalling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization.
Purification Method: | Affinity purification |
Gene ID: | 11141 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |