The IL1RAP Polyclonal Antibody (CAB5349) is a valuable tool for researchers studying the interleukin-1 receptor accessory protein (IL1RAP), a key player in the immune response. This antibody, generated in rabbits, shows high reactivity with human samples and is validated for use in Western blotting applications. By binding to IL1RAP, it allows for the detection and analysis of this important protein in various cell types, making it ideal for studies in immunology and cancer research.IL1RAP is essential for the transmission of signals from the interleukin-1 receptor, leading to inflammatory responses and immune activation.
Its role in regulating the immune system makes it a target of interest for investigating diseases such as cancer, autoimmune disorders, and inflammatory conditions. Understanding the function of IL1RAP is crucial for the development of therapies that target or modulate the immune response in these disease contexts.Overall, the IL1RAP Polyclonal Antibody (CAB5349) is a reliable tool for researchers looking to study the role of IL1RAP in the immune response and its implications for disease pathology. It offers high specificity and sensitivity, making it a valuable asset for advancing immunological research.
Product Name:
IL1RAP Rabbit Polyclonal Antibody
SKU:
CAB5349
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-356 of human IL-1RAcP (NP_001161402.1).
Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
65kDa
Observed MW:
73kDa
This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.
Purification Method:
Affinity purification
Gene ID:
3556
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using IL-1RAcP Rabbit pAb (CAB5349) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
