IL1R2 Rabbit Polyclonal Antibody (CAB1899)
- SKU:
- CAB1899
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | IL1R2 Rabbit Polyclonal Antibody |
SKU: | CAB1899 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human IL1R2 (NP_775465.1). |
Sequence: | AHTG AARS CRFR GRHY KREF RLEG EPVA LRCP QVPY WLWA SVSP RINL TWHK NDSA RTVP GEEE TRMW AQDG ALWL LPAL QEDS GTYV CTTR NASY CDKM SIEL RVFE NTDA FLPF ISYP QILT LSTS GVLV CPDL SEFT RDKT DVKI QWYK DSLL LDKD NEKF LSVR GTTH LLVH DVAL EDAG YYRC VLTF AHEG QQYN ITRS IELR IKKK KEET IPVI ISPL KTIS ASLG SRLT IPCK VFLG TGTP LTTM LWWT ANDT HIES AYPG GRVT EGPR QEYS ENNE NYIE VPLI FDPV TRED L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | IL1RB; CD121b; IL1R2c; CDw121b; IL-1R-2; IL-1RT2; IL-1RT-2; IL1R2 |
Positive Sample: | A-431,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 45kDa |
Observed MW: | 45kDa/60-70kDa/45kDa |
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.
Purification Method: | Affinity purification |
Gene ID: | 7850 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |