The IL1R1 Polyclonal Antibody (CAB5727) is a valuable tool for researchers studying IL1R1, a cell surface receptor involved in the immune response and inflammation. This antibody, developed in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.IL1R1, also known as interleukin-1 receptor type 1, plays a crucial role in mediating the effects of interleukin-1, a key pro-inflammatory cytokine. By binding to IL1R1, researchers can detect and analyze the protein in various cell types, providing insights into the mechanisms of immune signaling and inflammatory processes.
The IL1R1 Polyclonal Antibody is an essential tool for studies in immunology, inflammation, and related fields. Its specificity and reliability make it ideal for investigating the role of IL1R1 in diseases such as autoimmune disorders, chronic inflammatory conditions, and cancer. By understanding the function of IL1R1, researchers can pave the way for the development of novel therapies targeting immune-mediated diseases.
Product Name:
IL1R1 Rabbit Polyclonal Antibody
SKU:
CAB5727
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 380-569 of human IL1R1 (NP_000868.1).
Cell membrane, Membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
65kDa
Observed MW:
80kDa
This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12.
Purification Method:
Affinity purification
Gene ID:
3554
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse liver, using IL1R1 Rabbit pAb (CAB5727) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
