IL1B Antibody (PACO27601)
- SKU:
- PACO27601
- Product Type:
- Antibody
- Reactivity:
- Sheep
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
IL1B Antibody (PACO27601)
The IL1B Polyclonal Antibody (PACO27601) is a valuable tool for research involving IL1B, a key pro-inflammatory cytokine involved in the immune response. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the IL1B protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for studies in immunology, inflammation, and related fields.IL1B, also known as interleukin-1 beta, plays a crucial role in mediating inflammation and immune responses. Its dysregulation has been implicated in various diseases, including autoimmune disorders, sepsis, and inflammatory conditions.
Research into IL1B function is essential for developing targeted therapies to modulate inflammation and treat related diseases effectively.Overall, the IL1B Polyclonal Antibody (PACO27601) is a reliable tool for researchers seeking to explore the role of IL1B in immune response modulation and develop novel therapeutic interventions for inflammatory disorders. Its specificity and sensitivity make it a valuable asset in advancing our understanding of immune regulation and inflammatory pathways.
| Antibody Name: | IL1B Antibody (PACO27601) |
| Antibody SKU: | PACO27601 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Sheep |
| Immunogen: | Recombinant Sheep Interleukin-1 β protein (114-266AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: IL1B antibody at 2µg/ml + Recombinant Interleukin-1 beta protein 0.01µg Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 31 kDa Observed band size: 31 kDa . |
| Background: | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammat |
| Synonyms: | Interleukin-1 β (IL-1 beta), IL1B |
| UniProt Protein Function: | Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P21621 |
| NCBI GenInfo Identifier: | 57527829 |
| NCBI Gene ID: | 443539 |
| NCBI Accession: | NP_001009465.2 |
| UniProt Secondary Accession: | P21621 |
| UniProt Related Accession: | P21621 |
| Molecular Weight: | |
| NCBI Full Name: | interleukin-1 beta |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | IL1BÂ Â |
| NCBI Official Synonym Symbols: | IL-1BÂ Â |
| NCBI Protein Information: | interleukin-1 beta |
| UniProt Protein Name: | Interleukin-1 beta |
| UniProt Synonym Protein Names: | |
| Protein Family: | Interleukin |
| UniProt Gene Name: | IL1BÂ Â |
| UniProt Entry Name: |
Related Products
IL1B Antibody (PACO27597)
Canakinumab (Anti-IL1B) Biosimilar Antibody
Anti-IL1B Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0229)
Guinea pig IL1B ELISA Kit
IL 1 Beta Monoclonal Antibody [NYR-hIL1b] (CPAB0054)
