IL1B Antibody (PACO27597)
- SKU:
- PACO27597
- Product Type:
- Antibody
- Reactivity:
- Sheep
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
IL1B Antibody (PACO27597)
The IL1B Polyclonal Antibody (PAC027597) is an essential tool for researchers studying IL1B, an important cytokine involved in immune and inflammatory responses. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in a variety of applications, including Western blotting and immunohistochemistry.IL1B, also known as interleukin-1 beta, plays a key role in mediating the body's response to infection, injury, and inflammation. It is implicated in various diseases, including autoimmune disorders, inflammatory conditions, and cancer. By targeting IL1B, researchers can gain valuable insights into the mechanisms underlying these diseases and develop potential therapeutic strategies to target this cytokine.
The IL1B Polyclonal Antibody enables researchers to detect and analyze IL1B expression in different cell types, making it an invaluable tool for studies in immunology, inflammation, and cancer research. Understanding the role of IL1B in immune regulation and disease pathogenesis is essential for advancing our knowledge of these complex processes and ultimately developing targeted therapies for various health conditions.
| Antibody Name: | IL1B Antibody (PACO27597) |
| Antibody SKU: | PACO27597 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Sheep |
| Immunogen: | Recombinant Sheep Interleukin-1 β protein (114-266AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: IL1B antibody at 2µg/ml Lane 1: Recombinant Interleukin-1 beta protein 0.05µg Lane 2: Recombinant Interleukin-1 beta protein 0.5µg Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 31 kDa Observed band size: 31 kDa . |
| Synonyms: | Interleukin-1 β (IL-1 beta), IL1B |
| UniProt Protein Function: | Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P21621 |
| NCBI GenInfo Identifier: | 57527829 |
| NCBI Gene ID: | 443539 |
| NCBI Accession: | NP_001009465.2 |
| UniProt Secondary Accession: | P21621 |
| UniProt Related Accession: | P21621 |
| Molecular Weight: | |
| NCBI Full Name: | interleukin-1 beta |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | IL1BÂ Â |
| NCBI Official Synonym Symbols: | IL-1BÂ Â |
| NCBI Protein Information: | interleukin-1 beta |
| UniProt Protein Name: | Interleukin-1 beta |
| UniProt Synonym Protein Names: | |
| Protein Family: | Interleukin |
| UniProt Gene Name: | IL1BÂ Â |
| UniProt Entry Name: |
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