The IL1A Polyclonal Antibody (CAB1316) is a valuable tool for researchers studying IL1A, a pro-inflammatory cytokine involved in various immune responses and inflammatory processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards IL1A in human samples, making it suitable for use in Western blot applications. By targeting the IL1A protein, this antibody enables precise detection and analysis in a variety of cell types, providing researchers with crucial insights into the role of IL1A in immunology and disease pathogenesis.IL1A, also known as interleukin-1 alpha, is a key mediator of inflammation and immune regulation, playing a critical role in the body's defense against infections and injury. Dysregulation of IL1A has been implicated in the pathogenesis of various diseases, including autoimmune disorders, cardiovascular diseases, and cancer.
Therefore, studying the function and expression of IL1A is essential for developing targeted therapies aimed at modulating the immune response and treating inflammatory conditions.Overall, the IL1A Polyclonal Antibody (CAB1316) is a valuable tool for researchers investigating the complex interplay between IL1A and the immune system, offering a reliable means of characterizing IL1A expression and activity in disease contexts. Its use in research may lead to the development of novel therapeutic approaches that target IL1A signaling pathways, with the potential to revolutionize treatment strategies for a wide range of inflammatory and immune-related disorders
Product Name:
IL1A Rabbit Polyclonal Antibody
SKU:
CAB1316
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 113-267 of human IL-1 alpha (NP_000566.3).
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
Purification Method:
Affinity purification
Gene ID:
3552
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat lung, using IL-1 alpha Rabbit pAb (CAB1316) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
