IL1A Antibody (PACO27593)
- SKU:
- PACO27593
- Product Type:
- Antibody
- Reactivity:
- NHP - Rhesus Monkey
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
IL1A Antibody (PACO27593)
The IL1A Polyclonal Antibody (PACO27593) is a valuable tool for researchers studying IL1A, a cytokine involved in various immune and inflammatory responses. This antibody, produced in rabbits, exhibits high specificity for human samples and is validated for use in Western blot and immunohistochemistry applications.IL1A, also known as Interleukin-1 alpha, plays a crucial role in the regulation of immune and inflammatory processes. By targeting IL1A with this antibody, researchers can track and analyze its expression in different cell types, providing insights into its role in diseases such as arthritis, inflammatory bowel disease, and sepsis.
With its ability to detect and quantify IL1A, this antibody is a valuable tool for advancing research in immunology, inflammation, and related fields. Researchers can use it to better understand the mechanisms underlying immune responses and develop targeted therapies for diseases associated with dysregulated cytokine signaling.
| Antibody Name: | IL1A Antibody (PACO27593) |
| Antibody SKU: | PACO27593 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Macaca mulatta, Human |
| Immunogen: | Recombinant Macaca mulatta Interleukin-1 α protein (113-271AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: IL1A antibody at 6µg/ml Lane 1: Jurkat whole cell lysate Lane 2: Human placenta tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 31 kDa Observed band size: 31 kDa . |
| Background: | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
| Synonyms: | Interleukin-1 α (IL-1 alpha) (Hematopoietin-1), IL1A |
| UniProt Protein Function: | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P48089 |
| NCBI GenInfo Identifier: | 112363113 |
| NCBI Gene ID: | 700193 |
| NCBI Accession: | NP_001036222.1 |
| UniProt Secondary Accession: | P48089 |
| UniProt Related Accession: | P48089 |
| Molecular Weight: | 20.1 kDa |
| NCBI Full Name: | interleukin-1 alpha |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | IL1AÂ Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | interleukin-1 alpha |
| UniProt Protein Name: | Interleukin-1 alpha |
| UniProt Synonym Protein Names: | Hematopoietin-1 |
| Protein Family: | Interleukin |
| UniProt Gene Name: | IL1AÂ Â |
| UniProt Entry Name: | IL1A_MACMU |
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