IL18R1 Rabbit Polyclonal Antibody (CAB2706)
- SKU:
- CAB2706
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | IL18R1 Rabbit Polyclonal Antibody |
SKU: | CAB2706 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-320 of human IL18R1/IL-18 R alpha (NP_003846.1). |
Sequence: | AESC TSRP HITV VEGE PFYL KHCS CSLA HEIE TTTK SWYK SSGS QEHV ELNP RSSS RIAL HDCV LEFW PVEL NDTG SYFF QMKN YTQK WKLN VIRR NKHS CFTE RQVT SKIV EVKK FFQI TCEN SYYQ TLVN STSL YKNC KKLL LENN KNPT IKKN AEFE DQGY YSCV HFLH HNGK LFNI TKTF NITI VEDR SNIV PVLL GPKL NHVA VELG KNVR LNCS ALLN EEDV IYWM FGEE NGSD PNIH EEKE MRIM TPEG KWHA SKVL RIEN IGES NLNV LYNC TVAS TGGT DTKS FILV RKAD MA |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CD218a; IL18RA; IL1RRP; CDw218a; IL-1Rrp; IL-18Ralpha; IL18Ralpha2; IL-18R-alpha; IL18R1/IL-18 R alpha |
Positive Sample: | NCI-H460 |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 62kDa |
Observed MW: | 75kDa |
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8809 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |