The IL18R1 Polyclonal Antibody (CAB2706) is a valuable tool for researchers studying the IL18R1 protein, a receptor involved in the immune response and inflammation processes. This antibody, produced by Assay Genie, is specifically designed for use with human samples and has been validated for Western blot applications.IL18R1, also known as interleukin-18 receptor 1, plays a crucial role in mediating the effects of interleukin-18, a pro-inflammatory cytokine. By targeting IL18R1 with this polyclonal antibody, researchers can detect and analyze the expression of the receptor in various cell types, providing insights into its function in immunology and inflammatory conditions.
With its high reactivity and specificity for IL18R1, this antibody is a powerful tool for investigating the role of this receptor in diseases such as autoimmune disorders, inflammatory conditions, and cancer. By understanding the activity of IL18R1, researchers can develop new therapies that target the immune response and inflammation pathways, opening up new possibilities for disease treatment and management.
Product Name:
IL18R1 Rabbit Polyclonal Antibody
SKU:
CAB2706
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-320 of human IL18R1/IL-18 R alpha (NP_003846.1).
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8809
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from NCI-H460 cells, using IL18R1/IL-18 R alpha Rabbit pAb (CAB2706) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
