IL18R1/IL-18 R alpha Monoclonal Antibody (CAB22369)
The IL18R1 (IL-18 R alpha) Monoclonal Antibody (CAB22369) is a valuable tool for researchers studying the IL18R1 protein, which plays a key role in the immune response and inflammatory processes. This antibody, developed specifically for use in human samples, has been rigorously tested and validated for Western blot applications.IL18R1 is a receptor protein that binds to the cytokine IL-18, modulating the immune response and promoting inflammation. Dysregulation of IL18R1 signaling has been implicated in various diseases, including inflammatory conditions, autoimmune disorders, and cancer.
By targeting IL18R1 with this monoclonal antibody, researchers can gain insights into the molecular mechanisms underlying these diseases and explore potential therapeutic interventions.With its high specificity and sensitivity, the IL18R1 Monoclonal Antibody (CAB22369) is an essential tool for immunology and cancer research. By detecting and analyzing IL18R1 expression in different cell types, this antibody enables researchers to study the role of IL18R1 in immune regulation and inflammation, ultimately advancing our understanding of complex disease pathways.
Product Name:
IL18R1/IL-18 R alpha Monoclonal Antibody
SKU:
CAB22369
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 141-320 of human IL18R1/IL-18 R alpha (NP_003846.1).
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8809
Clone Number:
ARC52215
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using IL18R1/IL-18 R alpha Rabbit mAb (CAB22369) at 1:1800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
