IL18 Rabbit Polyclonal Antibody (CAB20473)
- SKU:
- CAB20473
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
Description
Product Name: | IL18 Rabbit Polyclonal Antibody |
SKU: | CAB20473 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 36-192 of mouse IL18 (NP_032386.1). |
Sequence: | NFGR LHCT TAVI RNIN DQVL FVDK RQPV FEDM TDID QSAS EPQT RLII YMYK DSEV RGLA VTLS VKDS KMST LSCK NKII SFEE MDPP ENID DIQS DLIF FQKR VPGH NKME FESS LYEG HFLA CQKE DDAF KLIL KKKD ENGD KSVM FTLT NLHQ S |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | Igif; Il-18; IL18 |
Positive Sample: | RAW264.7,Mouse spleen,Rat brain,Recombinant Human IL-18 Protein |
Conjugate: | Unconjugated |
Cellular Localization: | apical plasma membrane, cytoplasm, extracellular space |
Calculated MW: | 22kDa |
Observed MW: | 22kDa/18kDa |
Enables cytokine activity. Involved in lipid homeostasis; positive regulation of cell differentiation; and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including interleukin-18-mediated signaling pathway; positive regulation of NIK/NF-kappaB signaling; and positive regulation of interferon-gamma production. Located in extracellular space. Is expressed in several structures, including back skin; dorsal aorta; gut; lymphatic system; and reproductive system. Used to study atopic dermatitis. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; allergic rhinitis; autoimmune disease (multiple); biliary atresia; and hepatitis B. Orthologous to human IL18 (interleukin 18).
Purification Method: | Affinity purification |
Gene ID: | 16173 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |