IL18 Monoclonal Antibody [YNR-HIL18] (CPAB0047)
- SKU:
- CPAB0047
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- YNR-HIL18
- Applications:
- IP
- WB
- ELISA
Description
IL18 Monoclonal Antibody [YNR-HIL18] (CPAB0047)
The IL18 Polyclonal Antibody (CPAB0047) is a valuable tool for researchers studying interleukin-18 (IL-18), a proinflammatory cytokine involved in immune responses and inflammatory processes. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to IL-18, this antibody enables accurate detection and analysis in various cell types, making it an essential tool for studies in immunology and inflammation research.IL-18 is a key player in the regulation of immune responses, mediating both innate and adaptive immunity. Dysregulation of IL-18 signaling has been implicated in various inflammatory diseases, autoimmune disorders, and cancer.
Understanding the role of IL-18 in these pathological conditions is critical for the development of targeted therapies aimed at modulating immune responses and reducing inflammation.Overall, the IL18 Polyclonal Antibody (CPAB0047) is a reliable reagent for researchers investigating the function and regulation of IL-18 in health and disease. Its high specificity and sensitivity make it a valuable asset for studies aiming to unravel the complex interplay of cytokines in immune regulation and inflammation.
Product Name: | IL18 Antibody |
Product Sku: | CPAB0047 |
Size: | 0.5mg |
Host Species: | Mouse |
Immunogen: | r.Human IL-18 |
Clone: | YNR-HIL18. |
Reactivity: | Human |
Applications: | Immuneprecipitation, Western Blot, ELISA |
Purification Method: | Ion exchange |
Isotype: | IgG1 |
Background: | IL-18 is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. |
Synonyms: | Interferon-gamma-inducing factor, IGIF, IL-1g, IL-18, IL1F4, MGC12320, IFN-gamma-inducing factor, Interleukin-1 gamma, IL-1 gamma, Iboctadekin. |
Storage Buffer: | In lyophilized form, for long periods, store at 4C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20C. |