The IL17RD Polyclonal Antibody (CAB10031) is a valuable tool for studying the IL-17 receptor D protein, which is involved in immune regulation and inflammation. Developed using rabbit immunization, this antibody is highly specific to human samples and is validated for use in Western blot applications. By binding to the IL-17RD protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential component for studies in immunology and inflammatory diseases.
IL-17RD, a member of the IL-17 receptor family, plays a crucial role in mediating the effects of IL-17 cytokines in immune responses. Its involvement in inflammatory pathways makes it a promising target for research on autoimmune disorders, inflammatory conditions, and cancer. Understanding the functions of IL-17RD is key to developing new therapeutic strategies that modulate immune responses and control inflammation in these disease contexts.
Product Name:
IL17RD Rabbit Polyclonal Antibody
SKU:
CAB10031
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 150-300 of human IL17RD (NP_060033.3).
Cell membrane, Cytoplasm, Golgi apparatus membrane, Single-pass type I membrane protein, Single-pass type I membrane protein.
Calculated MW:
82kDa
Observed MW:
110kDa
This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
54756
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IL17RD antibody (CAB10031) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
